行政助理的主要職責包括協助 - (a) 辦公室的行政工作，包括處理各項文件及記錄、維持有效的檔案系統、制訂人手需要、編寫報告、制訂預算等； (b) 擔任有關的委員會或工作小組秘書工作，並協助預備會議文件及統籌相關的事宜； (c) 處理人事資源管理事宜； (d) 發展和管理電腦系統／數據庫的運作； (e) 舉辦和促進健康教育活動；以及 (f) 督導初級員工。

An Administrative Assistant mainly assists in - (a) general administration and renovation work of the office, including handling all aspects of correspondence and documentation, maintaining an effective filing system, working out manpower requirements, and preparing reports and budgets, etc.; (b) serving as secretary and preparing discussion paper of committees or working groups, coordination work and making logistic arrangement of various meetings; (c) handling human resources management matters; (d) systems/ database development and management; (e) organising and promoting public health programmes; and (f) the supervision of junior staff.